Milk protein hydrolysate for addressing a bone or dental...

Details Milk protein hydrolysate for addressing a bone or dental... Milk protein hydrolysate for addressing a bone or dental...

A - Human Necessities

61

K

A61K 38/01 (2006.01) A23J 3/10 (2006.01) A23J 3/32 (2006.01) A23L 1/304 (2006.01) A23L 1/305 (2006.01) A61K 38/17 (2006.01) A61P 19/00 (2006.01)

Patent

CA 2360490

A composition for prevention or treatment of a bone or dental disorder which comprises a milk protein hydrolysate, use of the milk protein hydrolysate in the manufacture of a composition for the treatment or prevention of a bone or dental disorder, and a method of treatment which comprises administering an effective amount of a milk protein hydrolysate. In preferred embodiments the milk protein hydrolysate is a hydrolysate of casein, in particular a caseinoglycomacropeptide (CGMP), a mimetic, homologue or fragment thereof in a bioavailable form which retains the ability of CGMP to inhibit bone resorption or bone loss; or favor calcium absorption, retention or calcification; or a combination thereof.

L'invention concerne une composition pour la prévention ou le traitement d'une affection osseuse ou dentaire, composition comprenant un hydrolysat de protéine du lait, l'utilisation de l'hydrolysat de la protéine du lait dans la fabrication d'une composition pour le traitement ou la prévention d'une affection osseuse ou dentaire, ainsi qu'un procédé de traitement consistant à administrer une quantité efficace d'un hydrolysat de protéine du lait. Selon une forme d'exécution préférée, l'hydrolysat de protéine du lait est un hydrolysat de caséine, en particulier, un caséinoglycomacropeptide (CGMP), un mimétique, homologue ou fragment de celui-ci sous une forme biodisponible qui conserve l'aptitude du CGMP à inhiber la résorption ou une perte osseuse, ou l'absorption, la rétention de calcium favorable ou la calcification, ou une combinaison de ces propriétés.

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