Immunomodulatory complex and use thereof in diseases caused...

A - Human Necessities – 61 – K

Patent

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A61K 39/106 (2006.01) A61K 35/74 (2006.01) A61K 39/09 (2006.01) A61K 39/102 (2006.01) A61K 39/116 (2006.01) A61K 39/39 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2246744

A therapeutical vaccine complex having activity specific for Helicobacter bacteria as well as non-specific immunomodulation activity for regulating the natural defences of the body, is disclosed. The drug is also useful for preventing relapses, particularly in cases of resistance to conventional treatment. The drug essentially consists of RNA, selective membrane fractions of microbial germs, particular amino acid sequences, sodium chloride and a steroidal anti-inflammatory in predetermined proportions enabling simultaneous delivery of antibiotics and frenosecretories. Said drug is particularly suitable for treating digestive tract diseases caused by Helicobacter (antral gastritis, duodenal ulcers, gastric ulcers, oesophagitis, hepatitis) and preventing stomach cancer and degenerative infectious MALT (mucosa-associated lymphoid tissue) lymphoma, as well as coronary diseases directly or indirectly dependent on Helicobacter infections.

Complexe vaccinal thérapeutique spécifique des bactéries Helicobacter et non spécifique agissant par immunomodulation permettant la régulation des défenses naturelles de l'organisme. Ce médicament permet également d'éviter les récidives, notamment dans les cas de résistances aux traitements conventionnels. Il est composé essentiellement d'ARN, de fractions sélectives membranaires de germes microbiens, de séquences particulières d'acides aminés, de chlorure de sodium et d'anti-inflammatoire stéroïdien, dans des proportions déterminées, permettant l'administration simultanée d'antibiotiques et d'antisécrétoires. Ce médicament est particulièrement destiné au traitement des maladies du tractus digestif par Helicobacter (gastrites antrales, ulcère duodénal, ulcère gastrique, oesophagite, hépatite) et à la prévention du cancer gastrique et du lymphome de Malt ("mucous associated lymphoid tissue") d'origine infectieuse dégénérative, ainsi que des affections coronariennes directement ou indirectement dépendantes d'infections par Helicobacter.

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