C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/06 (2006.01) A61K 31/165 (2006.01)
Patent
CA 2136008
The invention provides new compounds of formula (I) wherein o is an integer of 1 to 4; each of R and R1, which may be the same or different, is hydrogen, halogen, trifluoromethyl or C1-C4 alkoxy; R2 is hydrogen or C1-C4 alkyl; and a pharmaceutically acceptable salt thereof; and wherein when, at the same time, R is hydrogen, R1 is hydrogen or halogen and n is one, then R2 is other than hydrogen or methyl; and of formula (IA) wherein R3 is halogen, and a pharmaceutically acceptable salt thereof, which are active on the central nervous system (CNS) and can be used in therapy as anti-epileptics, anti-Parkinson, neuroprotective, antidepressant, anti-spastic anal hypnotic agents.
Bonsignori Alberto
Dostert Philippe
Pevarello Paolo
Varasi Mario
Farmitalia Carlo Erba S.r.l.
Fetherstonhaugh & Co.
Newron Pharmaceuticals S.p.a.
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