Skin care compositions and their use in healing injured skin

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/685 (2006.01) A61K 8/36 (2006.01) A61K 8/37 (2006.01) A61K 8/55 (2006.01) A61K 8/63 (2006.01) A61K 8/68 (2006.01) A61K 31/13 (2006.01) A61K 45/06 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2281430

Disclosed are skin care compositions and their use in healing injured skin. The compositions are identical in lipid constituents and structural property to epidermal membranes. They comprise the major constituents for membranes of the stratum corneum, including ceramides, cholesterol and fatty acids, the major constituents for endodermal membranes, including lecithin and triglyceride, and physiological active substances, including phytosphingosine and its derivatives. Without causing side effects, the skin care compositions are far superior in skin penetration and water-retention capacity. With the same composition and structural properties as in epidermal membranes, the compositions fortify the intercellular, lamellar bilayer sheets of the stratum corneum to function as the epidermal barrier, resulting in a great reduction of transcutaneous water loss and in showing an excellent hydration and emolliation effect on the epidermis. Also, the skin care compositions are of good compatibility with therapeutic active ingredients whether hydrophobic or hydrophilic, as well as of excellent drug delivery. So, they are very effective for healing injured skin and acne.

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