Remedies for eating disorders

Details Remedies for eating disorders Remedies for eating disorders

A - Human Necessities

61

K

A61K 38/27 (2006.01)

Patent

CA 2260148

This invention relates to a therapeutic agent for the treatment of abnormal eating behavior. The psychotic symptoms characteristic of anorexia nervosa such as apocleisis, intentional vomiting, eating in secret and the like have been treated with tranquilizers and the like, but the effectiveness was only limited. By administration of a therapeutic agent according to the present invention, i.e., a human growth hormone (hGH) formulation, a will to eat can spontaneously be developed in a patient who previously received nutrition only passively by means of a forcible nutrition program or a nasal nutrition supply. It is effective especially against, the eating disorder anorexia nervosa, attributable possibly to an increased central growth hormone releasing factor (GRH)-hGH secretion system.

Médicaments visant les anomalies du comportement alimentaire liées à l'anorexie mentale. Bien qu'il soit devenu habituel d'utiliser des tranquillisants, etc., pour traiter les symptômes psychiques propres à l'anorexie mentale caractérisée par des anomalies du comportement alimentaire, telles que le refus des aliments, les vomissements provoqués et le fait de manger en cachette, les résultats obtenus sont médiocres. L'administration des médicaments ci-dessus, c'est-à-dire de préparations à base d'hormone somatotrope humaine, permet de rendre l'envie de manger spontanée aux sujets qui ne pouvaient être nourris que par des moyens passifs, tels qu'éducation alimentaire forcée ou alimentation par sonde nasale. Ces médicaments sont particulièrement efficaces contre les troubles du comportement alimentaire de l'anorexie mentale basée apparemment sur une hyperactivité au niveau du système central de sécrétion du facteur de libération de l'hormone somatotrope (GH-RF).

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