C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/06 (2006.01) A61K 31/395 (2006.01) C07D 241/42 (2006.01) C07D 263/56 (2006.01) C07D 263/58 (2006.01) C07D 265/36 (2006.01) C07D 267/14 (2006.01) C07D 279/16 (2006.01) C07D 281/00 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2094767
Abstract of the Disclosure A compound of the formula: Image [I'] wherein ring A is an optionally substituted ben- zene ring; ring B' is an optionally substituted non- aromatic heterocyclic ring having, the same or differ- ent, two or more hetero atoms; R1 is a hydrogen atom or an optionally substituted hydrocarbon group, which may be different from one another in the repetition of n; Y is an optionally substituted amino group or an option- ally substituted N-containing saturated heterocyclic group; n denotes an integer of 1 to 10, provided that when the ring B' is a 5- to 7-membered ring, the ring B' contains at least one nitrogen atom as hetero atom and n denotes an integer of 2 to 10, or a salt thereof. The compounds and salts thereof have an excellent cholinesterase inhibitory activity and antidepressant activity, and are useful as therapeutic and/or prophy- lactic medicaments of senile dementia.
Goto Giichi
Ishihara Yuji
Miyamoto Masaomi
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
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