Use of 5-ht4 modulators for the manufacture of a medicament...

A - Human Necessities – 61 – K

Patent

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A61K 31/445 (2006.01) A61K 31/245 (2006.01) A61K 31/40 (2006.01) A61K 31/439 (2006.01)

Patent

CA 2126354

A compound which acts as an antagonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with bladder hypersensitivity, such as urinary incontinence, which is often associated with irritable bowel syndrome (IBS) and a compound which acts as an agonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with a poorly functioning bladder, such as urinary bladder hypoactivity following prostectomy.

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