Use of hemagglutinin of the african swine fever virus as an...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/62 (2006.01) C12N 5/078 (2010.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61P 37/04 (2006.01) C07K 14/01 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2684555

The invention generally concerns the use of of the haemoglutinin (HA) of the African swine pest virus (VPPA) as an adjuvant to promote the immune response to an antigen in a subject. The invention provides a genetic construction comprising all or part of the coding sequence of said HA fused with the coding sequence of an antigen. It has uses in human and animal health.

De manière générale, l'invention concerne l'utilisation de l'hémaglutinine (HA) du virus de la peste porcine africaine (VPPA) comme adjuvant pour potentialiser la réponse immunitaire contre un antigène chez un sujet. L'invention se rapporte à une construction génique comprenant la totalité ou une partie de la séquence codante de cette HA fusionnée à la séquence codante d'un antigène. Elle trouve une application dans la santé humaine et animale.

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