Treatment of leukocyte dysfunction with gm-csf

A - Human Necessities – 61 – K

Patent

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A61K 38/19 (2006.01)

Patent

CA 2045605

A method of treating leukocyte dysfunction in a mammal, preferably a human, wherein said dysfunction is associated with physical trauma, is disclosed. Preferably the method is used wherein the dysfunction is associated with thermal injury. The meth- od comprises administering to the mammal an effective amount of GM-CSF to potentiate the function of the dysfunctional leu- kocytes. The use of GM-CSF for the manufacture of a medicament for use in treating a patient having such leukocyte dysfunction and a pharmaceutical composition comprising GM-CSF for use in such treating are also disclosed.

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