Pharmaceutically active compounds

Details Pharmaceutically active compounds Pharmaceutically active compounds

C - Chemistry, Metallurgy

07

C

167/100, 530/5.0

C07C 323/58 (2006.01) C07C 323/60 (2006.01) C07C 327/30 (2006.01) C07C 327/32 (2006.01) C07D 207/10 (2006.01) C07D 207/12 (2006.01) C07D 207/16 (2006.01) C07D 277/06 (2006.01) C07F 9/38 (2006.01) C07F 9/572 (2006.01)

Patent

CA 2010353

Pharmaceutically active compounds Abstract There are described compounds of formula I, processes for their preparation and pharmaceutical formulations containing them, ZCHR1COR2 I in which R2 is a group of formula II, -NRxCHRyCOOH II in which Rx and Ry are each alkyl optionally substituted by phenyl; phenylalkyl C7 to 12, phenyl, phenyloxyalkyl, N-alkyl, O-alkyl, or together Rx and Ry may form a heterocyclic group optionally substituted by alkyl, phenyl; phenylalkyl C7 to 12, phenyl, phenyloxyalkyl, N-alkyl, O-alkyl, or one of Rx and Ry may be hydrogen, provided that one of Rx and Ry, the heterocyclic group formed by Rx and Ry or the optional substituents is substituted by one or two groups -COOR9 R9 is phenyl, -(CH2)xCONR14R15, -(CH2)yCOOR16 or alkyl optionally substituted by phenyl; R14, R15, R16, x and y, are as described in the specification, and pharmaceutically acceptable salts thereof.

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