Reductive amination of carbonylnitriles and similar compounds

Details Reductive amination of carbonylnitriles and similar compounds Reductive amination of carbonylnitriles and similar compounds

C - Chemistry, Metallurgy

07

C

260/605.4

C07C 209/48 (2006.01) C07C 211/36 (2006.01)

Patent

CA 2015252

- 47 - REDUCTIVE AMINATION OF CARBONYLNITRILES AND SIMILAR COMPOUNDS Abstract of the Disclosure Carbonylnitriles and iminonitriles are subjected to reductive amination in two steps, the first of which is at a temperature sufficient to produce the aminonitrile and the second of which is at a higher temperature and/or uses hydrogenation catalyst more reactive toward nitrile groups sufficient to produce the hydrogenated compound. The processes may be conducted under lower pressures, e.g., under about 700 psig, while maintaining desirable selectivity to the aminated product.

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