Replikin peptides and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/44 (2006.01) A61K 31/522 (2006.01) A61K 38/04 (2006.01) A61K 39/015 (2006.01) A61K 39/07 (2006.01) A61K 39/145 (2006.01) A61K 39/275 (2006.01) A61K 39/395 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 31/16 (2006.01) A61P 33/06 (2006.01) C07K 7/04 (2006.01) C07K 14/005 (2006.01) C07K 14/065 (2006.01) C07K 14/11 (2006.01) C07K 14/195 (2006.01) C07K 14/205 (2006.01) C07K 14/21 (2006.01) C07K 14/22 (2006.01) C07K 14/24 (2006.01) C07K 14/245 (2006.01) C07K 14/255 (2006.01) C07K 14/26 (2006.01

Patent

CA 2441540

Peptides of influenza virus hemagglutinin protein and Plasmodium falciparum malaria antigen, antibodies specific for the peptides, influenza vaccines, malaria vaccines and methods of stimulating the immune response of a subject to produce antibodies to influenza virus or malaria are disclosed. Also disclosed are methods for formulating vaccines for influenza virus. Isolated peptides of the Bacillus anthracis anthrax Toxin Lethal factor Protein pX01- 107, antibodies specific for the peptides and methods of stimulating the immune response of a subject to produce antibodies to the Bacillus anthracis Anthrax Toxin Lethal factor Protein pX01-107 are disclosed. Also disclosed are isolated peptides of the Small Pox Virus Surface Antigen S Precursor Protein, antibodies specific for the peptides and methods of stimulating the immune response of a subject to produce antibodies to the Small Pox Virus Surface Antigen S Precursor Protein.

L'invention concerne des peptides de protéines hemagglutinines du virus de la grippe, et des antigènes du paludisme Plasmodium falciparum, des anticorps spécifiques des peptides, des vaccins de la grippe, des vaccins du paludisme, ainsi que des procédés de stimulation de la réponse immunitaire d'un sujet à produire des anticorps pour le virus de la grippe ou le paludisme. L'invention concerne également des procédés de formulation de vaccins pour le virus de la grippe. L'invention concerne en outre des peptides isolés de la protéine pX01-107 facteur létal toxine du charbon Bacillus anthracis, des anticorps spécifiques des peptides, ainsi que des procédés de stimulation de la réponse immunitaire d'un sujet à produire des anticorps pour la protéine pX101-107 facteur létal toxine du charbon Bacillus anthracis. Enfin, l'invention concerne des peptides isolés de la protéine précurseur S de l'antigène superficiel micropoxvirus, des anticorps spécifiques des peptides, ainsi que des procédés de stimulation de la réponse immunitaire de protéine précurseur S d'antigène superficiel micropoxvirus.

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