Process for preparing 3-hydroxy 2-keto acids

Details Process for preparing 3-hydroxy 2-keto acids Process for preparing 3-hydroxy 2-keto acids

C - Chemistry, Metallurgy

07

C

260/519.1, 260/5

C07C 51/41 (2006.01) C07C 51/31 (2006.01) C07C 59/347 (2006.01) C07C 59/90 (2006.01) C07D 303/48 (2006.01)

Patent

CA 2020409

GC276 Abstract PROCESS FOR PREPARING 3-HYDROXY 2-KETO ACIDS A process has now been discovered by which an intermediate in preparation of antibiotics Image may be directly derived from the substrate Image by treatment with aqueous solutions of MHCO3 and MOH, wherein: R1, R2 and R3 are each independently alkyl, alkenyl, alkynyl, substituted alkyl, substituted alkenyl, substituted alkynyl, aryl, or substituted aryl; M is alkali metal (such as Na, Li, or K); and X is halogen.

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