Drug combination for the treatment of depression and related...

A - Human Necessities – 61 – K

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Details

A61K 31/55 (2006.01) A61K 31/506 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2396066

The invention relates to a combination comprising an amount of mirtazapine, or a pharmaceutically acceptable salt or solvate thereof, and an amount of gepirone, or a pharmaceutically acceptable salt or solvate thereof, optionally in association with one or more pharmaceutically acceptable carriers, whereby the amount of gepirone and the amount of mirtazapine are such that the effect of the composition is more favourable than the added effects of the amounts of each drug separately. This combination can be used in the treatment of depression and related disorders, whereby the invention also provides for a new method of treatment of depression and related disorders.

L'invention concerne une combinaison comprenant une certaine quantité de mirtazapine ou bien d'un sel ou d'un solvate de celle-ci pharmaceutiquement acceptable, et une certaine quantité de gepirone, ou bien d'un sel ou d'un solvate de celle-ci pharmaceutiquement acceptable, éventuellement en association avec un ou deux excipients pharmaceutiquement acceptables, la quantité de gepirone et la quantité de mirtazapine étant telles que l'effet de la composition est plus favorable que les effets additionnés des quantités de chaque médicament séparément. Ladite combinaison peut être utilisée dans le traitement de dépressions et de troubles s'y rapportant, la présente invention fournissant ainsi une nouvelle méthode de traitement des dépressions et des troubles s'y rapportant.

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