Linkers

Details Linkers Linkers

C - Chemistry, Metallurgy

07

F

C07F 7/08 (2006.01) C07C 227/18 (2006.01) C07C 229/02 (2006.01) C07H 9/04 (2006.01) C07J 1/00 (2006.01) C07J 9/00 (2006.01) C07J 41/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 2260736

The invention relates to a compound having the formula I (see fig. I), wherein R1 is hydroxy, (1-6C)alkoxy or NR4R5, R4 and R5 being independently hydrogen, (1-6C)alkyl, (3-7C)cycloalkyl, (2-6C)alkenyl, (4-6C)aryl or (5-7C)aralkyl, the aryl groups of which may be optionally substituted with halogen, (1-6C)alkyl or (1-6C)alkoxy; R2 is a halo atom, (1-8C)acyloxy, -O-C(O)-O-(1-6C)alkyl, -O-C(O)-O-(5- 7C)aralkyl, -SR6, -S(O)R6, -SeR6 or -Se(O)R6, R6 being (1-6C)alkyl or (4-6C)aryl; and R3 is -Si(R7)3, R7 being independently (1-6C)alkyl or (4-6C)aryl. The compounds of the invention may be used as protective groups or as linkers in solid phase organic chemistry.

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