Proteins related to gaba metabolism

C - Chemistry – Metallurgy – 12 – N

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C12N 15/53 (2006.01) C07K 16/40 (2006.01) C12N 9/04 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2368953

Novel polynucleotides encoding enzymes involved in the metabolism of gamma aminobutyric acid (GABA) in plants, specifically, gamma aminobutyric acid transaminase (GABA-T) and gamma hydroxybutyrate dehydrogenase (GHBDH), are described, as well as the GABA-T and GHBDH proteins they encode, and derived antibodies. The polynucleotides are useful for the screening and isolation of other related genes, the antibodies are useful for identifying and isolating related proteins, and the proteins provide a basis for determining how carbon and nitrogen is metabolized in plants.

Cette invention concerne de nouveaux polynucléotides codant pour des enzymes impliquées dans le métabolisme de l'acide gamma-aminobutyrique (GABA) dans des végétaux, en particulier la gamma aminobutyrique acide transaminase (GABA-T) et la gamma hydroxybutyrate déshydrogénase (GHBDH), ainsi que les protéines GABA-T et GHBDH pour lesquels ils codent, et les anticorps dérivés. Les polynucléotides conviennent au criblage et à l'isolation d'autres gènes correspondants, les anticorps conviennent à l'identification et l'isolation des protéines correspondantes, et les protéines sont un élément de base permettant de déterminer comment le carbone et l'azote sont métabolisés dans les végétaux.

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