Pyrrolidine dione derivatives

Details Pyrrolidine dione derivatives Pyrrolidine dione derivatives

C - Chemistry, Metallurgy

07

D

C07D 413/02 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07D 207/36 (2006.01) C07D 209/96 (2006.01) C07D 401/02 (2006.01) C07D 401/06 (2006.01) C07D 405/02 (2006.01) C07D 405/06 (2006.01) C07D 409/02 (2006.01) C07D 409/06 (2006.01) C07D 417/02 (2006.01) C07D 417/12 (2006.01) C07D 491/10 (2006.01) C07D 491/107 (2006.01) C07D 495/10 (2006.01)

Patent

CA 2091566

2091566 9206954 PCTABS00012 This invention relates to pyrrolidine dione derivatives of formula (I), (II) or (III), wherein R, R1, R3, R4, R5 and X are as defined below. These compounds are aldose reductase inhibitors and are useful in the treatment of diabetes associated complications such as neuropathy, nephropathy, retinopathy and cataracts. The invention also relates to compositions comprising the above compounds and methods for using those compositions in the treatment of the above diabetes associated complications.

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