Stereoselective and useful preparation of 3-substituted...

Details Stereoselective and useful preparation of 3-substituted... Stereoselective and useful preparation of 3-substituted...

C - Chemistry, Metallurgy

07

D

C07D 211/34 (2006.01) C07D 211/20 (2006.01) C07D 211/22 (2006.01) C07D 211/60 (2006.01) C07D 211/78 (2006.01) C07D 275/06 (2006.01) C07D 405/12 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07H 13/10 (2006.01)

Patent

CA 2212451

This invention relates to new stereoselective processes for preparing 3-substituted-4-aryl piperidines and methods for controlling the absolute stereochemistry at the C-3 and C-4 positions of the piperidine ring. Compounds of this type are key intermediates in the preparation of paroxetine, femoxetine,and other medicaments.

Cette invention concerne des nouveaux procédés stéréosélectifs de préparation de 4-aryl-pipéridines substituées en position 3 et des méthodes pour contrôler la stéréochimie absolue des positions 3 et 4 du cycle de la pipéridine. Les composés de ce type sont des intermédiaires clé pour la préparation de la paroxétine, de la femoxétine et d'autres médicaments.

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