Methods of treating bone-loss disorders using a gm-csf...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 19/10 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2711763

The invention is based on the discovery that GM-CSF antagonists can be used for the treatment of bone loss disorders, such as osteopenia. Accordingly, the invention provides methods of administering a GM-CSF antagonist, e.g., a GM-CSF antibody, to a patient that has a bone loss disorder and pharmaceutical compositions comprising such antagonists.

L'invention concerne des antagonistes GM-CSF pouvant être utilisés pour le traitement de troubles de la perte osseuse, tels que l'ostéopénie. En conséquence, l'invention fournit des procédés d'administration d'un antagoniste GM-CSF, par exemple un anticorps GM-CSF, à un patient qui présente des troubles de perte osseuse, et des compositions pharmaceutiques comprenant de tels antagonistes.

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