A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/107 (2006.01)
Patent
CA 2089003
A composition is disclosed containing non-esterified fatty acids having 14-18 carbon atoms, monoglycerides which are monoesters of glycerol and fatty acids having 14-18 carbon atoms, lysophosphatidylcholine in which the fatty acid moiety has 14-18 carbon atoms and bicarbonate. The compositions can optionally also contain bile salts. These compositions form submicron size colloidal particles and can act as vehicles for transporting orally administered drugs, sources of calories in the form of readily absorbable fats and as particles for topical. application to the skin. A method of making,these particles is also described.
Composition contenant des acides gras non estérifiés comportant 18 à 14 atomes de carbone, des monoglycérides qui sont des monoesters de glycérol et des acides gras comportant 14 à 18 atomes de carbone, un lysophosphatidylcholine dans lequel la fraction d'acides gras comporte 14 à 18 atomes de carbone ainsi que du bicarbonate. Les compositions peuvent également comprendre, facultativement, des sels biliaires. Ces compositions forment des particules colloïdales d'une taille inférieure au micron et peuvent faire office de véhicules dans le transport de médicaments administrés par voie orale, de sources de calories sous forme de matières grasses facilement absorbables, et de particules utilisées dans l'application locale sur la peau. L'invention concerne également un procédé de fabrication de ces particules.
Yesair David W.
Borden Ladner Gervais Llp
Yesair David W.
LandOfFree
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