A human sodium dependent phosphate transporter (ipt-1)

Details A human sodium dependent phosphate transporter (ipt-1) A human sodium dependent phosphate transporter (ipt-1)

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2231746

IPT-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IPT-1 polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal failure, end stage renal disease, uremic bone disease, and cancer, among others, and diagnostic assays for such conditions.

Divulgation de polypeptides et de polynucléotides IPT-1, ainsi que de méthodes de production de tels polypeptides par des techniques de recombinaison. Des méthodes sont également dévoilées pour utiliser de tels polypeptides et polynucléotides dans la conception de protocoles pour le traitement de l'insuffisance rénale chronique, du stade d'insuffisance rénale terminale, de la maladie osseuse urémique et du cancer, notamment, ainsi que des épreuves diagnostiques associées.

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