C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/14 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61P 25/28 (2006.01) C07D 401/12 (2006.01) C07D 413/04 (2006.01)
Patent
CA 2664130
The present invention is directed to compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
L'invention concerne des composés de la formule (I) qui sont des inhibiteurs de l'enzyme bêta-secrétase et qui sont utilisés pour traiter des maladies dans lesquelles l'enzyme bêta-secrétase est impliquée, telle la maladie d'Alzheimer. L'invention porte également sur des compositions pharmaceutiques renfermant lesdits composés et sur l'utilisation desdits composés et compositions pour traiter des maladies dans lesquelles l'enzyme bêta-secrétase est impliquée.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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