C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 25/28 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 15/13 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2646643
A method for treating a disease or disorder characterized by amyloid deposit of A-beta comprising administering to the subject a therapeutically effective amount of an antibody that binds specifically to RAGE and inhibits the binding of a RAGE binding partner.
La présente invention concerne un procédé de traitement d'une maladie ou d'une affection caractérisée par un dépôt amyloïde de A-bêta, ledit procédé comprenant l'administration au sujet d'une quantité thérapeutiquement efficace d'un anticorps qui se lie spécifiquement à un RAGE et qui inhibe la liaison d'un partenaire de liaison du RAGE.
Jacobsen Jack Steven
Kodangattil Sreekumar Raman
Tan Xiang-Yang
Tchistiakova Lioudmila
Widom Angela
Smart & Biggar
Wyeth
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