C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 249/04 (2006.01) A61K 31/4192 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2581126
The subject invention provides CAI compounds and formulations thereof, and methods for their use in the localized treatment of non-life threatening diseases. Formulations of CAI compounds of the subject invention include CAI free base and CAI prodrug microcrystallines, microparticles, emulsions, and the like. The subject invention further provides methods for treating non-life threatening diseases using the CAI compounds of the invention (i.e., novel delivery systems and combination therapies), that are effective and are associated with little or no adverse side effects.
La présente invention concerne des composés CAI (carboxyamidotriazole) ainsi que leurs formulations et des méthodes d'utilisation de ceux-ci dans le traitement localisé de maladies ne mettant pas la vie en danger. Les formulations de composés CAI de la présente invention contiennent une base exempte de CAI ainsi que des microcristallines, des microparticules, des émulsions et analogues de promédicaments de CAI. La présente invention concerne également des méthodes de traitement de maladies ne mettant pas la vie en danger à l'aide des composés CAI de l'invention (c'est-à-dire de nouveaux systèmes d'administration ainsi que des thérapies combinées) qui sont efficaces et présentent peu ou pas d'effets secondaires indésirables.
Franklin Alan J.
Jurczyk Simona
Robinson Gary
Shapiro Gideon
Mbm Intellectual Property Law Llp
Rfe Pharma Llc
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