Adsorbent for toxic shock syndrome toxin-1, method for...

A - Human Necessities – 61 – K

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A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 35/26 (2006.01) A61M 1/36 (2006.01) B01D 15/00 (2006.01) B01D 15/08 (2006.01) B01J 20/22 (2006.01) B01J 20/32 (2006.01)

Patent

CA 2287169

Adsorbents for toxic shock syndrome toxin-1 (TSST-1) composed of a water- insoluble carrier and a compound which is immobilized thereon and has a log P (wherein P means the partition coefficient in an octanol-water system) of at least 2.50; a method for eliminating TSST-1 in bodily fluids, characterized by bringing bodily fluids containing TSST-1 into contact with the above-mentioned adsorbents; adsorbers for TSST-1 comprising a container which is packed with the above adsorbents and provided with an inlet and an outlet of bodily fluids and a means for preventing the leakage of the adsorbents therefrom; and use of the above adsorbents. By using these adsorbents, TSST-1 in bodily fluids can be efficiently adsorbed and eliminated.

Adsorbants de la toxine-1 du syndrome de choc toxique (TSST-1) composés d'un excipient non hydrosoluble et d'un composé qui est immobilisé sur l'excipient et possède un log P (P étant le coefficient de partage dans un système octanol-eau) d'au moins 2,50; procédé d'élimination de la TSST-1 dans des fluides corporels, qui consiste à mettre les fluides contenant la TSST-1 en contact avec les adsorbants susmentionnés; adsorbeurs pour la TSST-1 comportant un récipient rempli desdits absorbants et doté d'un orifice d'entrée et d'un orifice de sortie de fluides corporels et d'un moyen destiné à empêcher la fuite des adsorbants par lesdits orifices, et utilisation desdits adsorbants. Ces adsorbants permettent l'adsorption et l'élimination efficaces de la TSST-1 de fluides corporels.

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