Humanized anti-lymphotoxin beta receptor antibodies

Details Humanized anti-lymphotoxin beta receptor antibodies Humanized anti-lymphotoxin beta receptor antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) C12N 5/12 (2006.01)

Patent

CA 2491480

This invention concerns humanized antibodies specific for the lymphotoxin beta receptor (LT-.beta.-R), cell lines that produce these antibodies, immunochemicals made from the antibodies, and diagnostic methods that use the antibodies. The invention also relates to the use of the antibodies alone or in combination with chemotherapeutic agent(s) in therapeutic methods.

Cette invention concerne des anticorps humanisés spécifiques du récepteur de la lymphotoxine bêta (LT-?-R), des lignées cellulaires produisant ces anticorps, des produits immunochimiques fabriqués à partir de ces anticorps, et des méthodes diagnostiques utilisant ces anticorps. L'invention concerne également l'utilisation d'anticorps seuls ou en association avec un (des) agent(s) chimiothérapeutique(s) dans des méthodes thérapeutiques.

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