Non-aggregated pharmaceutically active peptide

Details Non-aggregated pharmaceutically active peptide Non-aggregated pharmaceutically active peptide

A - Human Necessities

61

K

A61K 47/26 (2006.01) A61P 31/18 (2006.01) A61K 38/08 (2006.01)

Patent

CA 2714867

The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example insulin and Peptide T or analog thereof.

La présente invention concerne des compositions contenant des alkylglycosides et des procédés destinés à accroître la stabilité, à réduire l'agrégation et l'immunogénicité, à intensifier l'activité biologique, et à réduire ou à prévenir une formation fibrillaire d'un peptide, d'un polypeptide, ou d'un de leurs variants, par exemple l'insuline et le peptide T ou leurs analogues.

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