Methods and compositions for optimization of oxygen...

A - Human Necessities – 61 – K

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A61K 38/16 (2006.01) A61K 35/14 (2006.01) A61K 38/42 (2006.01)

Patent

CA 2282407

Compositions, and methods of use thereof, for use as blood substitute products comprise aqueous mixtures of oxygen-carrying and non-oxygen carrying plasma expanders and methods for the use thereof. The oxygen-carrying component may consist of and hemoglobin-based oxygen carrier, while the non-oxygen carrying plasma expander may consist of any suitable diluent.

L'invention concerne des compositions et des procédés d'utilisation de celles-ci, ces compositions étant destinées à être utilisées en tant que produit sanguins de remplacement, et renfermant des mélanges aqueux de succédanés du plasma sanguin transportant de l'oxygène et des mélanges aqueux de succédanés du plasma sanguin ne transportant pas d'oxygène. L'invention concerne également les procédés d'utilisation de ces mélanges. Le constituant transportant de l'oxygène peut être n'importe quel vecteur d'oxygène à base d'hémoglobine, tandis que le succédané de plasma sanguin ne transportant pas d'oxygène peut être n'importe quel diluant approprié.

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