Sustained delivery of an active agent using an implantable...

Details Sustained delivery of an active agent using an implantable... Sustained delivery of an active agent using an implantable...

A - Human Necessities

61

M

A61M 31/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2244997

The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water- swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.

L'invention concerne un dispositif d'administration d'une formulation d'agent actif pendant une durée d'administration prédéterminée. Un réservoir imperméable est divisé en une chambre d'agent gonflant au contact de l'eau et une chambre de formulation d'agent actif. Le fluide provenant du milieu permet une imbibition à travers un bouchon semi-perméable à l'intérieur de la chambre d'agent gonflant au contact de l'eau et la formulation d'agent actif est libérée par une sortie régulatrice à diffusion en retour. On peut atteindre des durées d'administration allant jusqu'à 2 ans.

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