Therapeutic and diagnostic methods using total leukocyte...

Details Therapeutic and diagnostic methods using total leukocyte... Therapeutic and diagnostic methods using total leukocyte...

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/531 (2006.01) G01N 33/542 (2006.01) G01N 33/543 (2006.01) G01N 33/564 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/571 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) G01N 33/58 (2006.01) G01N 33/96 (2006.01)

Patent

CA 2095626

The invention relates to the measurement of total leukocyte antigens, or fragments thereof, and the use of such measure- ments to enumerate cells, especially in whole blood. The term "total" leukocyte antigen used herein refers to the total amount of a leukocyte antigen in a sample, including that present in membrane and intracellular compartments and extracellular soluble com- partments. Measurements of a total leukocyte antigen can be used to type cells, detect or diagnose disease or to monitor disease therapy. In a further embodiment, the invention relates to the measurement of both the amount of total leukocyte antigen and the amount of the soluble form of the leukocyte antigen and a comparison of the measured levels.

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