Liquid antacid compositions

Details Liquid antacid compositions Liquid antacid compositions

A - Human Necessities

61

K

A61K 33/10 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01)

Patent

CA 2162248

Liquid antacid compositions for neutralizing stomach acid in humans and other animals comprising: (a) calcium carbonate; (b) short chain alkyl esters of p-hydroxybenzoic acid; (c) benzyl alcohol; (d) optionally, but preferably, bis-biguanide compound or a pharmaceutically- acceptable salt thereof; and (e) other excipients. These compositions are further preferably formulated to contain an elevated soluble solids content at a level which will increase the shelf stability of the composition.

Une composition liquide antiacide destinée à neutraliser l'acidité de l'estomac chez l'homme et l'animal comprend: (a) du carbonate de calcium; (b) des esters d'alkyle à chaîne courte de l'acide p-hydroxybenzoïque; (c) de l'alcool benzylique; (d) à titre facultatif, mais de préférence, un composé bis-guanide ou un sel de celui-ci acceptable sur le plan pharmaceutique; et (e) d'autres excipients. Ces compositions sont en outre formulées de préférence pour avoir une teneur suffisamment élevée en matières solides solubles, dont le niveau augmente la stabilité de conservation de la composition.

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