Intracellular glucocorticoid-induced leucine zippers...

Details Intracellular glucocorticoid-induced leucine zippers... Intracellular glucocorticoid-induced leucine zippers...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2287906

A DNA sequence encoding a glucocorticoid-induced leucine-zipper family related protein (GILR), isoforms, fragments or analogs thereof, said GILR, isoforms, fragments or analogs thereof capable of inhibiting apoptosis and stimulating lymphocyte activity, GILR proteins, isoforms, analogs, fragments and derivatives thereof encoded by the aforesaid DNA sequence, their preparation and uses.

L'invention concerne une séquence d'ADN codant pour une protéine (GILR) associée à la famille des glissières à leucine et induite par un glucocorticoïde, pour des isoformes, fragments ou analogues de cette protéine, cette protéine GILR, des isoformes, fragments ou analogues de celle-ci étant capables d'inhiber l'apoptose et de stimuler l'activité des lymphocytes. L'invention concerne également des protéines GILR, des isoformes, analogues, fragments et dérivés de celles-ci, codés par ladite séquence d'ADN, ainsi que la préparation et les utilisations de ceux-ci.

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