Method and apparatus to reduce false positive and false...

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 31/00 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2577145

A method, computer program medium, and system for analyzing a protein sample that obtains a mass spectrum of the derived peptides, and determines from the mass spectrum a first set of peptide identifications for the peptides. In the method, computer program medium, and system, incorrect identifications can be filtered from the first set of peptide identifications by removal from the first set those peptide identifications ascertained to be false identifications; and the filtered first set can be filtered to generate a second set of the peptide identifications corresponding to the protein sample.

La présente invention concerne un procédé, un support à logiciel, et un système d'analyse d'un échantillon de protéine donnant un spectre de masse des peptides dérivés, et en détermine un premier ensemble d'identifications de peptides. L'invention permet de filtrer les identifications erronées à partir du premier ensemble d'identifications de peptides, et ce, en retirant du premier ensemble les identifications dont il est vérifié que ce sont des identifications erronées. En outre, le premier ensemble ainsi filtré se prête à un autre filtrage permettant de générer un second ensemble d'identifications de peptides correspondant à l'échantillon de peptide.

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