C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/86 (2006.01) A61K 31/4164 (2006.01) C07D 233/74 (2006.01)
Patent
CA 2753425
Compositions, such as pharmaceutical compositions, comprising specific diarylhydantoin and diarylthiohydantoin compounds, or salts or solvates thereof, are provided. Isolated and purified forms of the compounds are also described, as are unit dosage forms, compositions of substantially pure compound and kits comprising the compounds. The compounds and pharmaceutical compositions thereof may find use in the prevention and/or treatment of a variety of conditions, including prostate cancer, Parkinson's disease, Alzheimer's disease, and others.
La présente invention concerne des compositions, par exemple des compositions pharmaceutiques, comprenant des composés spécifiques de type diarylhydantoïne et diarylthiohydantoïne ou, encore, des sels ou des solvates de ceux-ci. L'invention concerne également des formes isolées et purifiées desdits composés, de même que des formes pharmaceutiques en doses unitaires, des compositions à base de composés essentiellement purs et des nécessaires comprenant lesdits composés. Ces composés et les compositions pharmaceutiques en contenant peuvent être utilisés dans le cadre de la prévention et/ou du traitement de diverses affections, dont le cancer de la prostate, la maladie de Parkinson, la maladie d'Alzheimer et autres.
Gibbons Jacqueline A.
Jain Rajendra Parasmal
Borden Ladner Gervais Llp
Medivation Prostate Therapeutics Inc.
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