Immunoglobulin fc libraries

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 16/28 (2006.01)

Patent

CA 2685675

Methods and composition for the screening and isolation of aglycosylated antibody Fc domain polypeptides. For example, in certain aspects methods for identifying aglycosylated Fc domains that bind to Fc receptors or preferentially bind to particular Fc receptors are described. Furthermore, the invention provides aglycosylated Fc domains that bind to Fc receptors with high affinity. Enhanced methods and media for prokaryotic based interaction screening are also provided.

La présente invention concerne des procédés et une composition utilisée pour effectuer le clivage et l'isolement de polypeptides du domaine Fc d'anticorps aglycosylés. Par exemple, on décrit certains aspects qui portent sur des procédés d'identification de domaines Fc aglycosylés qui se lient aux récepteurs Fc ou qui se lient préférentiellement à des récepteurs Fc particuliers. De plus, cette invention concerne des domaines Fc aglycosylés qui se lient aux récepteurs Fc avec une forte affinité. On décrit également des procédés et des supports améliorés utiles pour le criblage des interactions reposant sur des procaryotes.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Immunoglobulin fc libraries does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunoglobulin fc libraries, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoglobulin fc libraries will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1393080

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.