Naphthylamides as central nervous system agents

Details Naphthylamides as central nervous system agents Naphthylamides as central nervous system agents

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) C07D 213/38 (2006.01) C07D 241/04 (2006.01) C07D 275/06 (2006.01) C07D 295/12 (2006.01) C07D 295/13 (2006.01) C07D 307/79 (2006.01) C07D 333/66 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2180155

Naphthylamides are described, as well as methods for the preparation and pharmaceutically composition of same, which are useful as central nervous system agents and are particularly useful as antipsychotic agents and as agents for the treatment of disorders which respond to dopaminergic blockade including psychotic depression, substance abuse, and compulsive disorders.

On décrit des naphtylamides, ainsi que des procédés destinés à leur préparation et des compositions pharmaceutiques les contenant. Ces compositions sont actives sur le système nerveux central, et elles sont particulièrement utiles en tant qu'agents antipsychotiques et comme agents pour le traitement de troubles qui découlent d'un blocage dopaminergique, tels que la dépression psychotique, les abus de diverses substances et des troubles du comportement du type compulsionnel.

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