Matrix metalloproteinase inhibitors of tgf .beta.-induced...

A - Human Necessities – 61 – K

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A61K 31/4045 (2006.01) A61F 2/16 (2006.01) A61K 31/16 (2006.01) A61K 38/55 (2006.01) A61K 45/06 (2006.01) A61P 27/12 (2006.01)

Patent

CA 2605783

The present invention provides novel methods and compositions for the treatment and/or prevention of cataracts. A composition that inhibits destabilization of E-cadherin is administered. Preferably the composition comprises a matrix metalloproteinase inhibitor.

Procédés et compositions pour le traitement et/ou la prévention de la cataracte. On administre une composition inhibant la déstabilisation de l'E-cadhérine, et de préférence ladite composition renferme un inhibiteur de métalloprotéinase matricielle.

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