Method for detecting maternally transferred drug metabolites...

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G01N 33/94 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2001229

A method for detecting the presence of drug metabolites in the meconium of newborn infants is described. The method involves separation of the drug metabolites from meconium in solution and then assaying the solution for the presence of the drug metabolites. The method is particularly useful for detection of cocaine, morphine and cannabinoids; however, any drug metabolite in the infant meconium can be tested. Conventional assay methods are used for the drug metabolites in the solutions derived from the meconium. The method provides a means for early detection of drug presence in infants which contribute to infant illness.

Méthode permettant de détecter la présence de métabolites de drogues dans le méconium des nouveau-nés. La méthode consiste à séparer les métabolites de drogues du méconium en solution, puis à doser la solution pour déceler la présence des métabolites en question. Particulièrement utile pour détecter la cocaïne, la morphine et les cannabinoïdes, cette méthode permet toutefois de détecter aussi tout métabolite de drogues présent dans le méconium du nourrisson. On a recours aux méthodes de dosage classiques pour détecter les métabolites de drogues dans les solutions dérivées du méconium. La méthode permet de détecter rapidement chez les nouveau-nés la présence de drogues qui contribuent à des maladies infantiles.

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