Surfactant protein-d for prevention and treatment of lung...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 11/00 (2006.01) A61P 31/00 (2006.01) C07K 14/785 (2006.01)

Patent

CA 2628472

Surfactant protein D (SP-D) is a member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Administration of SP-D protein or fragments thereof is useful for the prevention or treatment of sepsis or lung infection.

L'invention portant sur la protéine D surfactante (SP-D) est un élément de la famille des collectines des protéines collagènes contenant le domaine des lectines qui est exprimé dans des cellules épithéliales du poumon. L'administration de la protéine SP-D ou des fragments de celle-ci est utile dans la prévention ou le traitement de la sepsis ou des infections pulmonaires.

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