Diagnostic marker for ovarian cancer

Details Diagnostic marker for ovarian cancer Diagnostic marker for ovarian cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2537955

The present invention relates to methods of detecting, monitoring the efficacy of treatment of, and assessing the severity of ovarian cancer, by assessing the concentration of haptoglobin-1 precursor in a sample of biological fluid. The invention also relates to a kit comprising an antibody or nucleic acid probe specific for haptoglobin-1 precursor for use in the diagnosis of ovarian cancer, monitoring the efficacy of treatment of ovarian cancer, or assessing the severity of ovarian cancer.

La présente invention concerne des procédés pour détecter le cancer de l'ovaire, pour mesurer l'efficacité du traitement contre le cancer de l'ovaire, et connaître la gravité du cancer de l'ovaire. A cet effet, on mesure la concentration de précurseur de l'haptaglobine-1 dans un échantillon de fluide biologique. L'invention concerne également un nécessaire comprenant une sonde d'anticorps ou d'acide nucléique spécifique du précurseur de l'haptoglobine-1 convenant au diagnostic du cancer de l'ovaire, à la mesure de l'efficacité du traitement contre le cancer de l'ovaire, ou à la détermination de la gravité du cancer de l'ovaire.

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