Substituted 4-phenyltetrahydroisoquinolines, method of...

Details Substituted 4-phenyltetrahydroisoquinolines, method of... Substituted 4-phenyltetrahydroisoquinolines, method of...

C - Chemistry, Metallurgy

07

D

C07D 217/14 (2006.01) A61K 31/47 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2623462

The invention relates to compounds of the formula (I) where R1 to R8 have the meanings given in the claims. Medicaments which contain compounds of this type are useful in the prevention or treatment of diverse disorders. For instance the compounds may be used, inter alia, in kidney disorders such as acute or chronic kidney failure, in disorders of gall bladder function and in breathing disorders such as snoring or sleep apnoeas.

L'invention concerne des composés de formule (I), dans laquelle R1 à R8 ont les significations indiquées dans les revendications. Des médicaments, contenant des composés de ce type, sont utiles dans la prévention ou le traitement de diverses maladies. Ces composés s'utilisent, entre autres, dans le cas de maladies rénales telles que l'insuffisance rénale aiguë ou chronique, de troubles de la fonction biliaire et de troubles respiratoires, tels que le ronflement ou les apnées du sommeil.

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