A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61K 36/185 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2264577
Preparations and extracts of valerian, as well as isovaleramide, isovaleric acid, and its pharmaceutically acceptable salts, esters, and substituted amides, exhibit clinically significant pharmacological properties which implicate a treatment for a variety of pathological conditions, including spasticity and convulsions, which are ameliorated by effecting a mild depression of CNS activity. The compositions in question generally are non- cytotoxic and do not elicit weakness or sedative activity at doses that are effective for the symptomatic treatment of such pathological conditions.
Des préparations et des extraits de valériane, ainsi que d'isovaléramide, d'acide isovalérique et de leurs sels, esters et amides substitués pharmaceutiquement acceptables, présentent des propriétés pharmacologiques significatives d'un point de vue clinique, lesquelles impliquent un traitement de divers états pathologiques, notamment de la spasticité et des convulsions, états qui sont soulagés par une diminution douce de l'activité du système nerveux central. Les compositions en question sont, d'une manière générale, non cytotoxiques et elles ne provoquent pas d'activité de faiblesse ou sédative à des doses efficaces pour le traitement symptomatique de ces états pathologiques.
Artman Linda D.
Balandrin Manuel F.
Nps Pharmaceuticals Inc.
Robic
LandOfFree
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