4-amino-5-oxo-8-phenyl-5h-pyrido[2,3-d]pyrimidine...

Details 4-amino-5-oxo-8-phenyl-5h-pyrido[2,3-d]pyrimidine... 4-amino-5-oxo-8-phenyl-5h-pyrido[2,3-d]pyrimidine...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) C07C 275/28 (2006.01)

Patent

CA 2587609

Compounds of formula (I), where R6, R7, R8,R9,Het1, X and X' have the meanings given in claim 1 are tyrosine kinase inhibitors, in particular, of TIE-2, and Raf kinases and can be used, amongst other things, for the treatment of tumours.

L'invention concerne des composés de formule (I) dans laquelle R6, R7, R8, R9, Het1, X et X' sont tels que définis dans la première revendication. Ces composés sont des inhibiteurs des tyrosines kinases, en particulier de TIE-2, et des kinases Raf, et peuvent notamment servir à traiter des tumeurs.

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