A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2429034
The present invention provides methods for inhibiting proliferation of astrocytes and astrocytic tumor cells. The present invention further provides methods for treating a condition associated with a defect in astrocyte proliferation in a subject, and methods for treating a condition associated with astrocytic tumor cell proliferation in a subject. Additionally, the present invention is directed to pharmaceutical compositions comprising CD81 protein or nucleic acid and a pharmaceutically-acceptable carrier. Finally, the present invention provides a method for determining whether a subject has an astrocytoma, and a method for assessing the efficacy of astrocytoma therapy in a subject.
La présente invention concerne des méthodes d'inhibition de la prolifération des astrocytes et des cellules tumorales astrocytiques. L'invention concerne également des méthodes de traitement d'un état pathologique associé à un défaut dans la prolifération des astrocytes chez un sujet. De plus, la présente invention concerne des compositions pharmaceutiques comprenant une protéine CD81 ou un acide nucléique et un excipient acceptable d'un point de vue pharmaceutique. La présente invention concerne enfin une méthode permettant de déterminer si un sujet est atteint d'un astrocytome, et une méthode d'évaluation de l'efficacité d'une thérapie de traitement de l'astrocytome.
Albert Einstein College Of Medicine Of Yeshiva University
Gowling Lafleur Henderson Llp
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