Use of a peptide as a therapeutic agent

Details Use of a peptide as a therapeutic agent Use of a peptide as a therapeutic agent

A - Human Necessities

61

K

A61K 38/29 (2006.01) A61K 38/22 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/28 (2006.01) A61P 31/00 (2006.01) A61P 31/04 (2006.01) A61P 31/20 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2699020

The present invention is directed to the use of the combination of the peptide compounds Ala-Val-Ser-Glu-His-Gln- Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp- Leu-Arg-Arg-Arg-Phe-Phe-Leu-His- His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-OH and Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly- Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 as a therapeutic combination for prophylaxis and/or treatment of cancer, a heart and vascular disease, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, or an autoimmune disease.

La présente invention concerne l'utilisation de la combinaison des composés peptidiques Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-lle-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-lle-Ala-Glu-lle-His-Thr-Ala-OH et VaI-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 en tant que composés polythérapeutiques destinés à la prophylaxie et/ou au traitement du cancer, d'une maladie cardiaque et vasculaire, d'une maladie infectieuse, d'une maladie fibreuse, d'une maladie inflammatoire, d'une maladie neurodégénérative ou d'une maladie auto-immune.

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