Treatment of canine hemangiosarcoma with a histone...

A - Human Necessities – 61 – K

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A61K 31/16 (2006.01)

Patent

CA 2517346

The present invention is directed to a method of treating cancer, particularly canine hemangiosarcoma. The method includes the continuous and regular administration of a formulation including a histone deacetylase inhibitor as part of the standard canine diet. The preferred histone deacetylase inhibitor is SAHA. The formulation is administered following splenectomy to prevent tumor recurrence.

La présente invention a trait à un procédé de traitement de cancer, notamment d'hémangiosarcome canin. Le procédé comprend l'administration continue et régulière d'une formulation comportant un inhibiteur d'histone déacétylase comme faisant partie du régime standard canin. L'inhibiteur d'histone déacétylase préféré est l'acide suberoylanilide hydroxamique (SAHA). La formulation est administrée suite à une splénectomie pour éviter la récidive tumorale.

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