Compositions and methods for immunotherapy

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) A61K 31/7004 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2757437

The present invention provides novel immunotherapeutic compositions and methods useful for treating or preventing microbial infections, weakened immune systems, diseases in which cells have become obligately anerobic and cellular proliferative disorders including cancer. The immunotherapeutics herein use benzaldehyde derivatives, precursors and intermediaries alone or in combination with additional therapeutic agents to stimulate the immune system and inhibit cellular proliferation. The immunotherapeutics of the present invention are particularly useful in the treatment of microbial infections and cellular proliferative disorders which are resistant to traditional methods of treatment such as antibiotics and chemotherapy.

La présente invention porte sur de nouvelles compositions immunothérapeutiques et sur des procédés utiles pour traiter ou prévenir des infections microbiennes, des systèmes immunitaires affaiblis, des maladies dans lesquelles des cellules sont devenues obligatoirement anaérobies et des troubles prolifératifs cellulaires comprenant le cancer. L'immunothérapie utilise ici des dérivés de benzaldéhyde, des précurseurs et des intermédiaires individuellement ou en combinaison avec des agents thérapeutiques supplémentaires pour stimuler le système immunitaire et inhiber la prolifération cellulaire. L'immunothérapie de la présente invention est particulièrement utile dans le traitement d'infections microbiennes et de troubles de la prolifération cellulaire qui sont résistants à des procédés traditionnels de traitement tels que des antibiotiques et une chimiothérapie.

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