Benzamide derivatives as inhibitors of histone deacetylase

Details Benzamide derivatives as inhibitors of histone deacetylase Benzamide derivatives as inhibitors of histone deacetylase

C - Chemistry, Metallurgy

07

D

C07D 207/32 (2006.01) C07D 213/40 (2006.01) C07D 213/56 (2006.01) C07D 213/61 (2006.01) C07D 295/14 (2006.01) C07D 307/52 (2006.01) C07D 317/58 (2006.01) C07D 333/28 (2006.01) C07D 333/36 (2006.01) C07D 333/38 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2648804

The invention relates to the inhibition of histone deacetylase. The invention provides compounds which are derivatives of benzamide and suitable in methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions .

L'invention concerne l'inhibition de l'histone désacétylase. L'invention porte en outre sur des composés qui sont des dérivés de benzamide et sont appropriés pour être utilisés dans des procédés permettant d'inhiber l'activité enzymatique de l'histone désacétylase. L'invention concerne également des compositions et des procédés permettant de traiter des maladies et des pathologies associées à une prolifération cellulaire.

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