Substance exhibiting neuromodulator activity

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4015 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2647512

The invention relates to medicine, in particular to pharmacology and to medicinal agents exhibiting a neurotropic and cerebrovascular activity. The novelty of the invention consists in that an N-carbomoyl-methyl-4-phenyl-2-pyrrolidon agent injected into an organism displays an universal pronounced effect in the form of the one hundred percent survival of animals, eliminates the development of a neurological symptom complex of a cerebral stroke of different aetiologies, localizes a cerebral affection area and the destructive development thereof. It is proved, that the inventive agent exhibits universal neurotropic (neuromodulator) activity and produces a neuroprotective-cerebrovascular action.

L'invention concerne la médecine et plus particulièrement la pharmacologie; elle porte sur des médicaments possédant une activité neurotrope et cérébrovasculaire. L'invention consiste en ce que l'introduction dans le corps de N-carbomoyl-méthyl-4-phényl-2-pyrrolidon lors d'un ACV expérimental hémorragique ou ischémique assure un effet exprimé universellement qui se manifeste en une survie de 100 % des animaux; il écarte le développement d'un complexe de symptômes neurologique d'un ACV d'étiologie différente et limite la zone affectée du cerveau et son développement destructeur. La substance de l'invention présente une activité neurotrope universelle (neuromodulatrice) et possède un effet neuroprotecteur et cérébrovasculaire.

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