A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/66 (2006.01) A61K 9/08 (2006.01) A61P 19/08 (2006.01)
Patent
CA 2345364
The invention concerns the use of a bisphosphonic acid derivative of formula (I) wherein: R1 represents a hydrogen atom, a halogen atom, a hydroxyl, an amino, a monoalky(C1-C4)amino, a dialkyl(C1-C4) amino; R2 represents a halogen atom, a C1-C5 linear alkyl substituted or not substituted by a group selected among a chlorine atom, a hydroxyl, an amino, a monoalkyl(C1-C4)amino, a dialky(C1-C4)amino; a cycloalkyl(C3-C7)amino; or R2 represents a phenoxy, a phenyl, a thiol, a phenylthio, a chlorophenylthio, a pyridyl, a pyridylmethyl, a 1-pyridyl-1-hydroxymethyl, an imidazolylmethyl, a thiomorpholin-4-yl or one of its pharmaceutically acceptable salts or one of its hydrates for preparing a medicine for treating lameness related to osteoarthrosis, osteochondrosis, or enthesopathy of bone insertions of tendons, ligaments or aponeurosis in an animal not suffering from arthritis or fractures or exostosis.
L'invention concerne l'utilisation d'un dérivé de l'acide bisphosphonique de formule (I) dans laquelle: Ri représente un atome d'hydrogène, un atome d'halogène, un hydroxyle, un amino, un monoalkyl(C1- C4)amino, un dialkyl(C1-C4)amino; R2 représente un atome d'halogène, un alkyle linéaire comportant de 1 à 5 atomes de carbone non substitué ou substitué par un groupe choisi parmi un atome de chlore, un hydroxyle, un amino, un monoalkyl(C1-C4)amino, un dialkyl(C1- C4)amino; un cycloalkyl(C3-C7)amino, ou R2 représente un phénoxy, un phényle, un thiol, un phénylthio, un chlorophénylthio, un pyridyle, un pyridylméthyle, un 1-pyridyl-1-hydroxyméthyle, un imidazolylméthyle, un thiomorpholin-4-yle d'un de ses sels pharmaceutiquement acceptables ou d'un de ses hydrates dans la préparation d'un médicament destiné au traitement des boiteries apparaissant lors d'ostéo- arthrose, d'ostéochondrose, ou d'enthésopathies des insertions osseuses des tendons, des ligaments ou des aponévroses chez l'animal ne souffrant ni d'arthrite, ni de fractures, ni d'exostoses.
Bardon Thierry
Du Mesnil Philippe
Thiebaud Dominique
Ceva Sante Animale
Robic
LandOfFree
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